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Remove the EpiPen® Auto-Injector from the carrier tube and follow these. 2 simple steps: After administration, patients should seek medical attention ORANGE TIP into thigh at 90? angle and hold in place for 10 seconds. Each EpiPen® can only be used once. If symptoms don't improve, you can administer a second EpiPen® after 5-15 minutes. Remove the EpiPen® from the carry case. 3 Mar 2014 Show yourself or others how to use the EpiPen (epinephrine) Auto-Injector in the event of a severe allergic reaction. Learn more at EpiPen.ca. 5 Oct 2017 Changes to instructions on the administration of EpiPen® and EpiPen® Junior adrenaline autoinjector. Mylan UK has recently received an EpiPen – find out how to use an EpiPen; Jext – find out how to use Jext Instructions are also included on the side of each injector if you forget how to use it or 23 Nov 2011National Guidelines - Always Carry Two EpiPen® People who have been prescribed an adrenaline auto-injector because of the risk of anaphylaxis should Stay lying down or seated and have someone stay with you until you have been assessed by a paramedic. Unconscious patients should be placed in the recovery position. Place the orange tip on a hard surface, squeeze the sides of the orange tip and push down. If you have any side effects, these should be reported directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard/ or search for MHRA Yellow Card in