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GUIDELINE FORTHE USE OF DEPOT &. LONG ACTING INJECTABLE ANTIPSYCHOTICS. 1. Approved by MHLD DT August 2018. Ratified by ADTC November Guidance on the Administration to Adults of Oil-based Depot and other Long-Acting Intramuscular. Antipsychotic Injections. 5th. Edition. June. 2016. Janssen Evidence-based information on guidelines for the administrations of depot injections from hundreds of trustworthy sources for health and social care. 20 Dec 2013 Keywords: Guidelines, Long-acting injectable, Depot formulation, Long-acting injectable (LAI) antipsychotics have been part of the 5 Jan 2018 Association of UK University Hospitals. Guidelines for the Administration of. Long Acting Antipsychotic Injections in Adults. (Version 5 – January Information on taking antipsychotic medication through depot injection. UHB Incident Form HS /IDO/07. • Guidance on the Administration to Adults of Oil-based. Depot and other Long-Acting Intramuscular Antipsychotic. Injections For depot antipsychotics—side-effects may persist until the drug has been cleared Other drugs in the class antipsychotics, first-generation (depot injections).There is no evidence to suggest that effectiveness is improved by increasing the frequency of injections. • Injections are painful and injection sites may cause Refer to NHS Lothian advice: “Depot Antipsychotic Guidelines”. Depot injections should be initiated on specialist advice, for the patient's convenience or to