Results. Over the 28-day trial there was significant improvement in both depressive symptoms (F 5,35 =8.03, p=0.002, ? 2 =0.534) and symptoms of anxiety (F 5,35 =14.275, p<0.001, ? 2 =0.67) for the eight subjects that completed the trial. One hundred percent of subjects completing the trial responded to ketamine for both anxiety and depression.

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