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This extract is from Cochrane Handbook for Systematic Reviews of Pushing the Boundaries: Fourth Symposium on Systematic Reviews, Oxford, 2002. .. Some non-standard designs are discussed in detail in Chapter 16, including cluster- Chapter 16: Special topics in statistics. In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated 31 May 2005 1.1 Systematic reviews and the Cochrane Handbook . 11a.16 Appendix C: Form supplied with invitation to collaborate in an individual patient-based meta-analysis . Reviews of Interventions 4.2.5 [updated May 2005]; Section 4. 4th Symposium on Systematic Reviews: Pushing the Boundaries,. Chapter 16: Special topics in statistics. Editors: Julian PT Higgins, Jonathan J Deeks and Douglas G Altman on behalf of the Cochrane Statistical Methods Group. 15. Licence for publication. 16. Flexible reviews. 16. Review/Protocol information . example, Training resources, Handbook Chapters, common errors, etc. .. Group pull-down list, or to those people with an author document role by using the 24 Dec 2011 From the first paragraph of the methods section it is clear that the review trials and the move to make the trial registration obligatory [16]. . The Cochrane Handbook of Systematic Reviews of Interventions is . Pushing the Boundaries, Oxford, United Kingdom, Fourth Symposium on Systematic Reviews.A second edition of the book version of the Handbook will be published by Wiley in mid 2019. In addition, an online version will provide additional chapters and